How does the tetrahydrofuran analog 1 compare in potency to meayamycin?

Label:chem

Topic
A study investigated the antiproliferative activity of tetrahydrofuran analog 1 in human colon cancer cell lines (HCT-116, LS174T) and human lung cancer cell line (A549), using meayamycin and doxorubicin as controls.
Answer
The tetrahydrofuran analog 1 was found to be three orders of magnitude less potent than meayamycin. While less potent, it still exhibits low micromolar growth inhibition.
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