What is the role of NaN3 in the synthesis of 1H-tetrazoles using the CoFe2O4@HPECG/Pr-SO3H$Cu(II) catalyst?
Label:chem
Topic
Sodium azide (NaN3) is a common reagent used in the synthesis of tetrazoles.
Answer
NaN3 serves as a nitrogen source in the synthesis of 1H-tetrazoles. It reacts with nitriles in the presence of the CoFe2O4@HPECG/Pr-SO3H$Cu(II) catalyst to form the tetrazole ring structure through a [3+2] cycloaddition reaction.
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