How does Bisphenol S (BPS) influence DNMT1 gene expression in trophoblastic cells?

Label:chem

Topic
DNMT1 is a DNA methyltransferase involved in epigenetic regulation and placental development.
Answer
BPS exposure modulates DNMT1 expression in a nonlinear manner. Expression peaked at 0.25 μg/mL BPS and declined at higher concentrations, indicating a potential compensatory epigenetic response at low doses and cytotoxic suppression at high doses.
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