What is the impact of OpCBR1 on root growth in Ophiorrhiza pumila?

Label:chem

Topic
Ophiorrhiza pumila is a valuable plant for the production of the anti-cancer drug camptothecin. Understanding the factors that influence its growth and metabolism is crucial for optimizing camptothecin production. OpCBR1, an ERF transcription factor, has been identified as a regulator of camptothecin biosynthesis, but its effect on root growth was not fully understood.
Answer
Overexpression of OpCBR1 in O. pumila hairy roots promotes root growth by upregulating auxin and cytokinin-related genes, leading to enhanced biomass. This suggests that OpCBR1 can be used to improve root growth and biomass, which could potentially increase camptothecin yield through biomass engineering.
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