Why is acetone challenging to detect in breath?

Label:chem

Topic
Acetone is volatile and can be lost during sample pretreatment in breath analysis, and it can also diffuse from exhaled breath into saliva.
Answer
Detecting acetone in breath requires complex headspace sample handling, a method where acetone can be lost during sample pretreatment. Additionally, acetone's volatility allows it to diffuse from exhaled breath into the oral cavity and dissolve in saliva, making breath analysis more challenging.
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