What is Afamelanotide and its properties?

Label:chem

Topic
Compound: Afamelanotide
Answer
Afamelanotide is currently the only approved drug therapy for erythropoietic protoporphyria, having greater affinity for its target and a longer biological half-life. It interacted with the target with a score of 7.4 kcal/mol. Despite being a peptide analogue of alpha melanocyte-stimulating hormone (a-MSH), it is more resistant to degradation by serum and proteolytic enzymes, and is thus expected to resist degradation by COVID-19 protease. Its dock score was -7.4.
Return to Home Chemical List
Knowledge you may be interested in
What is Ombitasvir and its use in treating hepatitis C? What is Dasabuvir and its use in treating hepatitis C? What is Grazoprevir and its use in treating hepatitis C? What is K-11777 and its potential as an antiviral agent? What is Angiotensin II human acetate and its binding affinity? What is Velpatasvir and its use in treating hepatitis C? What is Daclatasvir and its use in treating hepatitis C? What is Elbasvir and its role in treating hepatitis C? What is Paritaprevir and its use in treating hepatitis C? What is Glecaprevir and its use in treating hepatitis C? What is Camostat and its potential as a protease inhibitor? What is Lopinavir and its use in treating HIV and its repurposing for COVID-19? What is Indinavir and its use in treating HIV? What is Ritonavir and its use in treating HIV, and its potential for COVID-19? What is Gonadorelin and its mechanism of action? Why was anhydrous form I of dabigatran etexilate mesylate chosen for development despite anhydrous form II being thermodynamically more stable? How do the crystalline forms of dabigatran etexilate mesylate differ structurally and how were these differences characterized? What are the solubility characteristics of dabigatran etexilate mesylate and what phenomenon occurs in aqueous media at higher pH values? Why is Phenobarbital considered a highly cost-effective treatment for early and established Status Epilepticus (SE)? What are the key pharmacological characteristics of phenobarbital?