What is Ledipasvir and its relevance to hepatitis C and potential for COVID-19 treatment?

Label:chem

Topic
Compound: Ledipasvir
Answer
Ledipasvir is a direct-acting antiviral (DAA) used in combinations to treat chronic HCV genotypes 1, 4, 5, and 6. Its mechanism of action is postulated to prevent hyper-phosphorylation of NS5A, essential for viral protein reproduction, RNA replication, and assembly of HCV virions. In this study, it showed a high binding affinity of 9.4 with COVID-19 protease, making it a promising candidate for COVID-19 protease inhibition.
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