What is Simeprevir and its relevance to hepatitis C and potential for COVID-19 treatment?

Label:chem

Topic
Compound: Simeprevir
Answer
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor, FDA-approved in November 2014, marketed as Olysio® for chronic HCV genotype 1 or 4 infection. In this study, it showed a high binding affinity of 9.5 with COVID-19 protease, suggesting it as a promising candidate for COVID-19 protease inhibition.
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