Trifluridine
CAS number: 70-00-8
Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to [idoxuridine]. It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. It displays effective antiviral activity against Herpes simplex virus type 1 and 2.
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Fluorinated purine and pyrimidine antimetabolites clinically used for the treatment of numerous cancers and viral infections: Fluorouracil, capecitabine, gemcitabine, fludarabine, flucytosine, elvucitabine, tezacitabine, trifluridine.
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