1,2,3-Trioxolane is a cyclic organic peroxide with a three-membered ring containing three oxygen atoms. It is also known as a molozonide and is an unstable intermediate formed during the ozonolysis of alkenes. This unstable intermediate quickly rearranges to form the more stable 1,2,4-trioxolane (ozonide).
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a) Artemisinin and its semisynthetic analogues. b) Comparison of tetraoxanes with trioxolane-based antimalarials.
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