Artemisinin
CAS number: 63968-64-9
(+)-artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial and a plant metabolite. It is a sesquiterpene lactone and an organic peroxide.
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a) Artemisinin and its semisynthetic analogues. b) Comparison of tetraoxanes with trioxolane-based antimalarials.
IC50 data against Cambodia–Thai patient isolates for 15 compared with other antimalarials. Blue: mefloquine; red: artesunate; green: artemisinin; purple: RKA182.
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