D-erythrose 4-phosphate is an erythrose phosphate that is D-erythrose carrying a phosphate group at position 4. It is an intermediate in the pentose phosphate pathway and Calvin cycle. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a D-erythrose. It is a conjugate acid of a D-erythrose 4-phosphate(2-).