A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
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Indole Alkaloids Bearing FIH Skeletons: (-)-Esermethole, (-)-Eseroline, (-)-physostigmine, (-)-Physovenine, Flustramine E, Flustramine B, Flustramine A, Aspidophyline A.