Proposed main metabolic pathway for Desoxypeganine 1 by microsomal enzymes.

Total ion chromatogram and extracted mass chromatograms obtained from an incubation mixture with Desoxypeganine 1. Peak 1 Vasicinone 3, Peak 2 Isovasicinone 4, Peak 3 Pegenone 2.

Lineweaver-Burk plot of C-oxidation of Desoxypeganine 1 measured by Pegenone 2 formation in the incubation mixtures containing the components described under Materials and methods. Mean values are presented from three determinations.