Perophoramidine is a complex, halogenated natural product isolated from a Philippine marine organism (ascidian) in 2002. It features a unique six-ring structure with two contiguous, or vicinal, quaternary centers and contains bromine, chlorine, and amidine groups. Perophoramidine exhibits cytotoxic activity against colon cancer cells by inducing apoptosis and has been the subject of significant interest in the field of synthetic organic chemistry for its complex structure.