Cyanamide is a nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an amino group. It has a role as an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. It is a nitrile and a one-carbon compound. It is a conjugate acid of a cyanamide(2-).
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Cyanation of the orthoesters 7. For the preparation of 8c and 8d, cyanoamine 1d (3.0 equiv.) and SiCl3OTf (3.0 equiv.) were used.
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