Lithium diisopropylamide
CAS number: 4111-54-0
Lithium diisopropylamide (LDA) is a prominent reagent used in organic synthesis. It is a hindered non-nucleophilic strong base that abstracts hydrogen from active carbon.
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Catalytic asymmetric synthesis of (S)-verapamil. LDA=lithium diisopropylamide.
![Azide–enolate [3+2] cycloaddition reactions implicated in amide and triazoline synthesis. LDA=lithium diisopropylamide, LHMDS=lithium hexamethyldisilazide.](http://www.wlxkc.cn/picture/1402519_01.png)
Azide–enolate [3+2] cycloaddition reactions implicated in amide and triazoline synthesis. LDA=lithium diisopropylamide, LHMDS=lithium hexamethyldisilazide.
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