Fmoc-phenylalanine is an essential amino acid derivative used in solid-phase peptide synthesis (SPPS) that has a protective Fmoc group attached to the amino group of phenylalanine. This modification makes it a stable building block for creating complex peptides, and it can be selectively removed when needed. Its applications include developing peptide-based drugs, creating novel materials for drug delivery, and researching protein interactions.
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Selected examples of pharmaceuticals and bioactive compounds that contain polycyclic aromatic hydrocarbon (PAH) scaffolds: Cyclophilin A inhibitor, Mycobacterium Tuberculosis Inhibitor, FMOC-PHENYLALANINE, Hsp90 inhibitor. The fluorene core is shown in red.
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