Mannose
CAS number: 3458-28-4
Mannose is a monosaccharide widely distributed in body fluids and tissues, especially in the nerve, skin, testicles, retina, liver and intestines. It is a simple sugar with a complex life. It's a welcome therapy for genetic and acquired human diseases, but it kills honeybees and blinds baby mice.
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Glycomimetic scaffolds designed to mimic (A) mannose and (B) fucose. Hydroxyl groups typically involved in C-type lectin binding are highlighted in red.
Synthesized pH-activatable mannose cluster-BODIPY-DCG-04 constructs (A) and a schematic overview of their expected internalization and fluorescence properties in mannose receptor expressing cells (B).
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