← Back to Chemical List
Etoposide
CAS number: 33419-42-0
Etoposide is a beta-D-glucoside, a furonaphthodioxole and an organic heterotetracyclic compound. It has a role as an antineoplastic agent and a DNA synthesis inhibitor. It is functionally related to a podophyllotoxin and a 4'-demethylepipodophyllotoxin.

Related images

Study of early signaling events of apoptosis induced by compound 6a in Jurkat cells. Cells treated with Etoposide were included as positive control.
Study of early signaling events of apoptosis induced by compound 6a in Jurkat cells. Cells treated with Etoposide were included as positive control.
Inhibition of topoisomerase by compounds 1-8. Native pBR322 plasmid DNA (-lane) was incubated with 4 units of topoisomerase I (Topo I) and II (Topo II) without (+lane), with control (CT-camptothecin or ET-etoposide), or with drug (lanes 1-8). DNA was analyzed by 1% agarose gel electrophoresis. The gel was stained with ethidium bromide and photographed under UV light.
Inhibition of topoisomerase by compounds 1-8. Native pBR322 plasmid DNA (-lane) was incubated with 4 units of topoisomerase I (Topo I) and II (Topo II) without (+lane), with control (CT-camptothecin or ET-etoposide), or with drug (lanes 1-8). DNA was analyzed by 1% agarose gel electrophoresis. The gel was stained with ethidium bromide and photographed under UV light.

Related Questions and Answers

No related questions yet