Trichloromethane is an organic chemical compound also known as chloroform. It is a volatile, colorless liquid with a sweet, ether-like odor. While historically used as an anesthetic, its main uses today are as a solvent, a chemical intermediate in various industrial processes, and a precursor in the production of refrigerants and PTFE.
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Although phosphonate 6 was acid labile and decomposed overnight in chloroform, it still underwent efficient cross-coupling reactions.
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