Hydrazine, anhydrous appears as a colorless, fuming oily liquid with an ammonia-like odor. It can cause cancer according to an independent committee of scientific and health experts.
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Hydrazine Scope
Modified diamine catalysts were synthesized starting from the commercial chiral diamine 2. All catalysts except 1a and 1k were easily prepared from 2 in a 4-step sequence as shown in Scheme 2.
Regioselective Synthetic Pathway for 1,3-Disubstituted Tetrahydroindazolones Using Hydrazines 1 and 2-(Hydroxy(N-Boc-pyrrolidin-2-yl)methylene)-5,5-dimethylcyclohexane-1,3-dione 3