3-Pyridinyl is a substituted pyridine ring in which a functional group is attached at the third carbon of the six-membered aromatic nitrogen-containing ring. The parent structure, pyridine, is similar to benzene but contains one nitrogen atom replacing a CH group, imparting basicity and unique reactivity. In the 3-pyridinyl configuration (also called meta-pyridyl), the substituent is bonded to the carbon atom adjacent to the nitrogen (but not directly next to it), influencing the molecule's electronic and steric properties. This moiety is commonly found in pharmaceuticals, agrochemicals, and ligands due to its ability to participate in hydrogen bonding, coordination chemistry, and π–π interactions.
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Synthesis of Pyridine Precursor 3
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