2-Cyclopropen-1-one
CAS number: 2961-80-0
2-Cyclopropen-1-one is a highly strained, three-membered cyclic ketone. As the smallest member of the cyclopropenone family, it consists of a cyclopropene ring bearing a carbonyl group, making it both aromatic and electrophilic.
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Photochemical decarbonylation of a cyclopropenone caged BCN probe (photo-DMBO) activates reactivity toward tetrazine-containing proteins, conferring spatial and temporal control over protein labeling.
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