1,3,4-Oxadiazole is a five-membered heterocyclic aromatic compound containing one oxygen atom and two nitrogen atoms, positioned at the 1, 3, and 4 positions. It's a key structural motif in many biologically active molecules and is known for its diverse pharmacological properties.
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The preparation of a representative small series of 1,3,4-oxadiazoles containing the 6-phenoxy-1,2,3,4-tetrahydronaphthalene side chain was conducted.