Febrifugine, a quinazolinone alkaloid that inhibits P. falciparum and has antimalarial activity, is an excellent compound that can be used to block the proliferation of malarial parasites.
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Initial approaches to febrifugine.
Synthesis of (+)-febrifugine.
Synthesis of ent-febrifugine.
Biologically active β-hydroxy piperidines.
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