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Doxorubicin
CAS number: 23214-92-8
Doxorubicin is a deoxy hexoside, an anthracycline, an anthracycline antibiotic, an aminoglycoside, a member of tetracenequinones, a member of p-quinones, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It has a role as an Escherichia coli metabolite. It is a conjugate base of a doxorubicin(1+). It derives from a hydride of a tetracene.

Related images

Structures of L-daunosamine 1, L-3-epi-daunosamine 2, L-ristosamine 3, L-acosamine 4, and the anthracycline antibiotics daunorubicin 5, doxorubicin 6, carubicin 7, idarubicin 8, and epirubicin 9.
Structures of L-daunosamine 1, L-3-epi-daunosamine 2, L-ristosamine 3, L-acosamine 4, and the anthracycline antibiotics daunorubicin 5, doxorubicin 6, carubicin 7, idarubicin 8, and epirubicin 9.
DOI: /10.1021/jo4020563

Related Questions and Answers

Q: How does doxorubicin contribute to the treatment of Hodgkin's lymphoma in both BV-AVD and ABVD regimens?
A: Doxorubicin provides a broad-spectrum cytotoxic effect in both regimens, contributing to the overall efficacy of the treatment by targeting rapidly dividing cancer cells.
Q: What is the role of doxorubicin in the aMVAC regimen?
A: Doxorubicin is administered at a dose of 30 mg/m² on day one of the biweekly cycles. It is an anthracycline antibiotic that helps in achieving tumor regression and is part of the combination therapy that enhances the overall efficacy of the regimen.