Amphidinol 3 (AM3) is a naturally occurring compound, specifically a polyene macrolide, produced by the marine dinoflagellate Amphidinium klebsii. It's known for its potent antifungal and hemolytic (blood cell-damaging) activities. AM3 achieves these effects by interacting with and permeabilizing cell membranes, forming pores in the process.
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Retrosynthetic analysis (Amphidinol 3).
Synthesis of the C(43)-C(67) Fragment of Am3(Amphidinol 3)
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