Synthesis of 2-phenyl-2,3-dihydroquinolin-4(1H)-one (2) from 2'-aminochalcone (1).
Kinetics curves of the yield to 2-phenyl-2,3-dihydroquinolin-4(1H)-one obtained with different solid acid catalysts (8 wt%) starting from 2'-Aminochalcone (1 mmol) in toluene (0.5 mL) at 1008C. MCM-41 (■), ITQ-2 (●), HBeta (▲), USY (◆), 15 wt% Mordenite (x), 15 wt% Sn-MCM-41(+).
Yield of 2-phenyl-2,3-dihydroquinolin-4(1H)-one (2) versus time obtained for HBeta (▲) and Betanano (■) using 2'-aminochalcone (1 mmol) in toluene (0.5 mL) at 1008C.
Yield of 2-phenyl-2,3-dihydroquinolin-4(1H)-one (2) versus time when the aza-Michael addition was performed using MCM-41 with different Si/Al ratios. Si/Al=15 (■), 30 (●), 50 (▲), Si-MCM-41 (◆). Reaction conditions: 2;-aminochalcone (1 mmol), MCM-41 (8 wt%), at 1008C, in toluene (0.5 mL).