Manzacidin A is a bromopyrrole alkaloid, a type of natural product found in marine sponges. It is characterized by its unique structure featuring a bromopyrrole carboxylic acid linked to a tetrahydropyrimidine ring, which includes a nitrogen-containing quaternary carbon stereocenter.
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Representative Natural Products and α-Alkyl Amino Acid Containing Quaternary Stereocenter with Nitrogen Substituent: Conagenin, manzacidin A, geranyllinaloisocyanide, alpha-methyl-D-phenylalanine
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