I-BET726, also known as GSK1324726A, is a selective inhibitor of BET (Bromodomain and Extra-Terminal domain) proteins. It was identified as a novel tetrahydroquinoline-based BET inhibitor, meaning it targets and inhibits the bromodomain-containing proteins BRD2, BRD3, and BRD4.
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Structures of selected published BET inhibitors and selected hydroxamic acid HDAC inhibitors.
DiscoveRx BROMOscan profile for I-BET726.
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