mGluR5 modulator 1
CAS number: 1261171-52-1
mGluR5 modulator 1 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 5 (mGluR5). This means it enhances the effects of the neurotransmitter glutamate at the mGluR5 receptor. It's primarily being researched for its potential in treating schizophrenia and cognitive impairments.
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![Autoradiography on horizontal rat brain slices, indicating heterogeneous distribution of activity with highest uptake in mGluR5-rich regions. The first and second rows represent application of 1 and 10 nM [18F]-16, respectively, and the first and second column represent baseline and blocking conditions, respectively.](http://www.wlxkc.cn/picture/5367115_16.png)
Autoradiography on horizontal rat brain slices, indicating heterogeneous distribution of activity with highest uptake in mGluR5-rich regions. The first and second rows represent application of 1 and 10 nM [18F]-16, respectively, and the first and second column represent baseline and blocking conditions, respectively.
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