Porothramycin A
CAS number: 110652-73-8
Porothramycin A is a type of pyrrolobenzodiazepine (PBD) antibiotic, specifically a monomeric PBD. It is a natural product produced by actinomycetes, a group of bacteria known for producing various bioactive compounds.
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Pyridinium ring-openings to form acyclic Zincke aldehydes, indoles, and dihydropyrroles relevant to the porothramycins. A ) activating group.
Formal Syntheses of Porothramycins A and B
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