Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family. It is a saturated organic heteromonocyclic parent and a member of morpholines. It is a conjugate base of a morpholinium.
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Aminocarbonylation of iodobenzene with morpholine.
(a) Solvent-free microwave-assisted reaction of aldehydes (1a, 2b-h) with morpholine (3) to give compounds 4a-h. (b) Hydrogen bonds exist in compounds 4b, 4c, and 4d.