2-Methoxy-5-methylpyridine-3-boronic acid pinacol ester, also known as 2-Methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine pinacol ester, is an organoboron compound featuring a pyridine ring substituted with a methoxy group at the 2-position, a methyl group at the 5-position, and a boronic ester moiety at the 3-position.
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Aryl and vinyl chlorides were cross-coupled with aryl and vinyl boronic acids, pinacol esters, and potassium trifluoroborate under nonbasic conditions mediated by 11. Yields are from isolated chromatographically homogeneous material (average of two runs) and were not optimized for time and catalyst loading.
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